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老化的眼睛

与年龄有关的常见眼病

精选于:PRIME 杂志,2 月 22 日

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  1. Reza HM、Ng BY、Phan TT、Tan DT、Beuerman RW、Ang LP。
    具有 CD227 阳性和独特模式的P63的新型脐带内膜细胞的特征。

        Stem Cell Reviews and Reports 2011 Sep;7(3):624-38

 

  1. Ang LPK、Reza HM、Tan XW、Do TP、Thein ZM、Yap C、Tan HK、Tan DTH、Beuerman RW。
    使用扩张结膜和角膜缘上皮细胞脐带血补充血清的培养基。

Invest. Ophthalmol. Vis. Sci 2011 Aug 3;52(9):6138-47

 

  1. Reza HM、Ng BY、Gimeno FL、Phan TT、Ang LP。

利用脐带膜干细胞开发生物工程细胞片,用于角膜缘干角膜再生兔眼细胞缺陷。 

Stem Cell Reviews and Reports 2011. 2011 Mar 10.

 

  1. Ang LP、Reza HM、Ng BY、Phan TT、Tan DT、Beuer man RW。

从人体脐带中分离和表征新型干细胞群。

Catalyst May 2011.

 

  1. Ang LPK、Tanioka H、Ang LPS、Do TP、Kawasaki S、Yamasaki K、Koizumi N、Nakamura T、Yokoi N、Komuro A、Inatomi T、Kinoshita S。

培养的人结膜上皮细胞移植用于全角膜缘干细胞的缺陷。 

Invest. Ophthalmol. Vis. Sci. 2010 51: 758-764.

 

  1. Ang LP、Reza HM、Ng BY、Phan TT、Tan DT、Beuerman RW。

从人脐带中分离和表征新型干细胞群。 Ann Acad Med Nov 2010;11s:S4.

 

  1. Lim LS、How AC、Ang LP、Tan DT。

Gundersen皮瓣治疗亚洲人群眼表疾病。ornea. 2009 Aug;28(7):747-51.

 

  1. Tong L、Chew J、Yang H、Ang LP、Tan DT、Beuerman RW。
    翼状胬肉形成和复发中的不同基因子集:使用全基因组表达数据剖析复杂的生物学现象。

MC Med Genomics. 2009 Mar 10;2:14.

 

  1. Zhou L、Beuerman RW、Ang LP、Chan CM、Li SF、Chew FT、Tan DT。
    翼状胬肉患者泪液中人α-防御素和 S100 钙结合蛋白 A8 和 A9 的升高。Invest Ophthalmol Vis Sci. 2009 May;50(5):2077-86.

 

  1. Ang LPK、Reza HM、Tan XW、Do TP、Thein ZM、Yap C、Tan HK、Tan DTH、Beuerman RW。

脐带血血清补充培养基用于结膜和角膜缘上皮细胞体外扩增的新用途。 Ann Acad Med Oct 2010;10s:S1.

 

  1. Ang LP、Sayegh RR、Foster SC、Dohlman CH。史蒂文斯-约翰逊综合症的波士顿角膜假体。American Journal of Ophthalmology 2008 Mar;145(3):438-44. Epub 2008.

 

  1. Ang LPS,Ang LP。目前对急性原发性闭角型青光眼治疗和结果的理解:亚洲视角。 Ann Acad Med Singapore. 2008 Mar;37(3):210-215.

 

  1. Ang LPK、Lim LS、Do TP、Thein Z、Cajucom-Uy H、R Beurman、Tan DTH。
    生物工程无血清衍生结膜上皮移植相当于治疗严重角膜和眼表疾病。Ann Acad Med Singapore Nov 2008; 11s: S2

 

  1. Tan DT、Janardhanan P、Zhou H、Chan YH、Htoon HM、Ang LP、Lim LS。亚洲人眼睛的穿透性角膜移植术新加坡角膜移植研究。Ophthalmology. 2007 Nov 29; [Epub ahead of print]

 

  1. Ang LP、Chua JL、Tan DT。

当前翼状胬肉治疗的概念和技术。 Curr Opin Ophthalmol. 2007 Jul;18(4):308-13.

 

  1. Ang LP, Higashihara H, Sotozono C, Shanmuganathan VA, Dua H, Tan DT, Kinoshita S. 氩激光虹膜切开术引起的大疱性角膜病变——一个在日本日益严重的问题。 Br J Ophthalmol. 2007 Jun 13; [Epub ahead of print]

 

  1. Ang LP、Lee MW、Seah LL、Cheong P、Rootman J. 眼周毛细血管瘤病灶内皮质类固醇注射后的眼眶蜂窝织炎。 Eye. 2007 Jul;21(7):999-1001.

 

  1. Sotozono C, Ang LP, Koizumi N, Higashihara H, Ueta M, Inatomi T, Yokoi N, Kaido M, Dogru M, Shimazaki J, Tsubota K, Yamada M, Kinoshita S. 

用于评估史蒂文斯-约翰逊综合征患者慢性眼部表现的新分级系统。 Ophthalmology 2007 Jul;114(7):1294-302

 

  1. Ghanem RC、de la Cruz J、Tobaigy FM、Ang LP、Azar DT。
    老视年龄组的 LASIK:40 至 69 岁患者的安全性、有效性和可预测性。 Ophthalmology2007 Jul;114(7):1303-10.

 

  1. Ang LPK、Nakamura T、Inatomi T、Sotozono C、Koizumi N、Kinoshita S. 

自体血清衍生的培养性口腔上皮移植治疗严重眼表疾病。 Archives of Ophthalmology 2006;124:1543-1551.

 

  1. Ang LPK、Sotozono C、Koizumi N、Suzuki T、Inatomi T、Kinoshita S。Stevens-Johnson 培养与传统角膜缘干细胞移植的比较史蒂文斯-约翰逊综合症。 American Journal of Ophthalmology 2007;143(1):178-80.

 

  1. Tanioka H、Kawasaki S、Yamasaki K、Ang LPK、Yokoi N、Komuro A、Inatomi T、Kinoshita S. 培养人结膜上皮细胞的建立自体角膜上皮移植的替代组织来源Invest Ophthalmol Vis Sci.2006 Sep ;47:3820-7.

 

  1. Tan CSH、Ang LPK、Choo CT、Cheah EST、Chee SP。

上表皮层里的眼眶囊肿——硅胶植入物的晚期并发症。  Ophthalmic plastic and reconstructive surgery 2006;22:398-400.

 

  1. Nakamura T、Inatomi T、Sotozono C、Ang LP、Koizumi N、Yokoi N、Kinoshita S. 自体血清衍生的培养角膜上皮等同物的移植用于治疗严重的眼表疾病。 Ophthalmology. 2006 Aug 11; [Epub ahead of print]

  2. Nakamura T、Ang LPK、Rigby H、Sekiyama E、Inatomi T、Sotozono C、Fullwood NJ、Kinoshita S。自体血清在史蒂文斯约翰逊综合征患者 角膜和口腔上皮等同物发育中的应用。  Invest Ophthalmol Vis Sci.2006 Mar;47(3):909-16.

 

  1. Nakamura T, Inatomi T, Sekiyama E, Ang LPK, Yokoi N, Kinoshita S. 无菌冻干羊膜治疗翼状胬肉的临床新应用。 Acta Ophthalmol Scand. 2006 Jun;84(3):401-5.

 

  1. Lim LS、Ho CL、Ang LP、Aung T、Tan DT。上虹膜激光周边虹膜切开术后下角膜失代偿。  American Journal of Ophthalmology2006 Jul;142(1):166-8.

 

  1. Friedman DS、Chew PT、Gazzard G、Ang LP、Lai YF、Quigley HA、Seah SK、Aung T。对侧眼急性原发性房角关闭后对侧眼的长期结果。 Ophthalmology. 2006 Jul;113(7):1087-91.

 

  1. Ang LPK. 角膜和眼表移植的进展。 SingVision Dec 2006.

 

  1. Ang LPK、Cheng ZY、Beuerman RW、Teoh SH、Zhu X、Tan DTH。
    使用无血清衍生的生物工程结膜上皮等效物来开发超薄的聚己内酯膜基材。 Investigative Ophthalmology and Visual Science 2006;47(1):105-12.

 

  1. Zhu X、Beuerman RW、Chan-Park MBE、Cheng ZY、Ang LPK、Tan DTH。
    增强组织生物膜的机械和生物学特性的眼表工程。 Annals Academy of Medicine 2006 Mar;35(3):210-5.

 

  1. Al-Tobaigy FM、Ang LPK、Ghanem RC、Azar DT。 

Epi-lasik 矫正近视的功效、可预测性和安全性。 手稿正在审核中。

 

  1. Ang LP。

角膜和眼表疾病治疗、干细胞移植和屈光手术。 SNEC CME Jun 2006.

  1. Zhou L、Beuerman RW、Foo YH、Liu SP、Ang LPK、Tan DTH。使用高分辨率质谱法表征人泪液蛋白。  Annals Academy of MedicineSingapore. 2006 Jun; 35:400-7.

 

  1. Ang LPK、Tan DTH、Cajucom-Uy H、Phan TT、R Beurman、R Lavker。

用于翼状胬肉手术的自体培养结膜移植。  American Journal of Ophthalmology 2005;139(4):611-619.

 

  1. Ang LPK、Tan DTH、Seah CJY、Beuerman RW。 人血清在支持人类体外和体内增殖中的用途结膜上皮细胞。 British Journal of Ophthalmology2005; 89:748-752.

 

  1. Ang LPK,Tan DTH。自体培养结膜移植治疗广泛复发性病毒性乳头状瘤。  American Journal of Ophthalmology2005; 140:136-138

 

  1. Ang LPK、Tan DTH、Phan TT、Beuerman RW、RM Lavker。 无血清培养人的体外和体内增殖能力的结膜上皮细胞。 Current Eye Research2004;28(5):307-317.

 

  1. Ang LPK、Tan DTH、Beuerman RW、Phan TT、RM Lavker。
    开发具有改善增殖特性的结膜上皮等效物的多步无血清培养系统。 Investigative Ophthalmology and Visual Science 2004;45(6):1789-1795.

 

  1. Tan DTH、Ang LPK、Beuerman RW。通过无血清衍生培养结膜上皮移植以重建眼表。 Transplantation2004;77(11):1729-1734.

 

  1. Tan DTH,Ang LPK。 自动板层角膜移植术治疗 PRK 术后角膜疤痕和变薄问题。 American Journal of Ophthalmology
    2004;138(6):1067-9.

 

  1. Tan DTH,Ang LPK。 改良的自动板层角膜移植术治疗圆锥角膜——一项新技术。 Cornea2006;25(10):1217-9.

  2. Zhou L、Huang LQ、Beuerman RWW、Grigg M、Li SFY、Chew FT、Ang LPK、Stern ME、Tan D. 人类眼泪的蛋白质组学分析:眼后防御素的表面手术。 Journal of Proteome Research 2004, 3(3): 410-416.

 

  1. Ang LPK、Aung T、Chua WH、Chew PTK。亚洲人群原发性闭角型青光眼的视野缺损:有症状
    和无症状疾病表现的比较研究。  Ophthalmology 2004; 111: 1636-40.

 

  1. Ang LPK、Tan DTH、Beuerman RW、RM Lavker。眼表上皮干细胞:对眼表稳态的影响,载于 Pfulgfelder S, Beuerman RW, Stern ME (eds).  Dry Eye and Ocular Surface Disorders. Marcel Dekker 2004. P225-46.

 

  1. Ang LPK、Tan DTH、Cajucon-Uy H、Phan TT、R Beurman、R Lavker。
    通过无血清衍生移植物重建眼表培养的结膜上皮等效物。 Annals Academy of Medicine 2004;33:S55-56.

 

  1. Ang LPK,Tan DTH。眼表干细胞与疾病:当前概念和临床应用。 Annals Academy of Medicine 2004;33(5):576-80.

 

  1. Ang LPK、Cheng ZY、Teoh SH、Zhu X、Beuerman RW、Tan DTH。使用超薄聚己内酯膜基质开发可移植的生物工程结膜等效物。  American Journal of Ophthalmology2005;139:s36-7.

 

  1. Ang LPK、Tan DTH、Beuerman RW、Phan TT、RM Lavker。 开发具有改善增殖能力的无血清衍生结膜等同物临床移植的特性。 American Journal of Ophthalmology2005;139:s36.

 

  1. Zhu X、Beuerman RW、Chan-Park MBE、Ang LPK、Tan DTH。 一种用于兔结膜组织工程的新型明胶-壳聚糖基质 。  American Journal of Ophthalmology2005;139:s43.

 

  1. Ang LPK、Tan DTH、Cajucom-Uy H、Phan TT、R Lavker、R Beurman。
    使用自体无血清培养结膜组织等效物眼表疾病的手术治疗。  American Journal of Ophthalmology2005;139:s10.

 

  1. Ang LPK,Tan DTH。眼睛的干细胞,新闻《干细胞:从实验室到临床》

 

  1. Aung T、Friedman DS、Chew PTK、Ang LPK、Gazzard G、Lai YF、Yip L、H Lai、Quigley H、Seah SKL。
    亚洲人急性原发性闭角性的长期结果。 Ophthalmology 2004;111:1464-9..

 

  1. Ang LPK、Yap EY、Fam HB。原发性抗磷脂综合征中的眼动脉和视网膜中央静脉阻塞。 Eye2004;18(4):439-440.

 

  1. Ang LPK、Tan DTH、Beuerman RW、Phan TT、RM Lavker。开发用于临床移植的自体无血清培养结膜等效物 ——一种治疗眼表疾病的新方法。 SGH Proceedings2003;12(3S):S76.

 

  1. Ang LPK、Phan TT、Tan DTH、Beuerman RW、Lavker RM。
    人结膜上皮细胞的无血清培养——眼表上皮细胞 新培养方法的开发。SGH Proceedings2003;12(3):161-169.

 

  1. SE Ti,Ang LPK,Tan DTH。眼表疾病, 临床眼科:亚洲视角新闻。

 

  1. Ang LPK、Abano J、Li L、Tan DTH。亚洲眼角膜移植, 临床眼科:亚洲视角新闻。

 

  1. Ang LPK,Tan DTH。眼睛的干细胞——一个有启发性的观点。 Singapore Medical Association News2003;35(6):8-9.

 

  1. M Rosman、Aung T、Ang LPK、Chew PTK、JM Liebmann、R Ritch。慢性闭角伴青光眼损伤:北美人群与亚洲人群的长期临床比较。 Ophthalmology2002;109(12)

 

  1. Aung T、Z Alsagoff、Ang LPK、Chew PTK。闭角型青光眼。 Ophthalmology2002;109:1-2.

 

  1. Tan, DT; Ang LPK; Theng, JTS; Gomezperalta, C; Cajucom-Uy, H; Beuerman, RW; Lavker, RM. 

自体培养结膜移植用于翼状胬肉手术。 Investigative Ophthalmology & Visual Science 2002;43:s121.

  1. Ang LPK、Aung T、Chew PTK。急性原发性闭角型青光眼:亚洲人群的长期眼压问题。 American Journal of Ophthalmology2001;1:7-12

 

  1. Ang LPK. 眼表干细胞——当前的概念和意义

Asia Pacific Biotech 2002;6(2):55

 

  1. Ang LPK、Aung T、Chew PTK。亚洲人群的急性原发性房角关闭:预防性激光周边虹膜切开术后对侧眼的长期结果。 Ophthalmolgy2000;107(11):2092-6

 

  1. Z Alsagoff、Aung T、Ang LPK、Chew PTK。亚洲人群原发性闭角型青光眼的长期临床过程。 Ophthalmology 2000;107:2300-4

 

  1. Ang LPK、Lee HM、Au Eong KG、Lim ATH、Yap EY。内源性克雷伯氏菌眼内炎。 Eye 2000;14(6):855-8

 

  1. Ang LPK、Yap EY、Fam HB。抗磷脂综合征双侧脉络膜梗死。 Clinical and Experimental Ophthalmology2000; 28(4): 326-8

 

  1. Ang LPK、Heng WJ、WK Chan。巩膜外神经纤维瘤。 International Ophthalmology1999;20:207-10

 

  1. Ang LPK、Sim DHJ、Chiang GSC、VSH Yong。虹膜 Varix。 Eye1997;11(5):733-5

 

  1. Ang LPK、Au Eong KG、SG Ong。带状疱疹眼科。 Journal Of Pediatric Ophthalmology & Strabismus2001;38(3):174-6

 

精选书籍章节

 

  1. Ang LPK、Tan DTH、Beuerman RW、RM Lavker。眼表上皮干细胞:对眼表稳态的影响,Pfulgfelder S,Beuerman

RW,Stern ME(编)。 干眼症和眼表疾病Marcel Dekker 2004. P225-46.

 

  1. Ang LPK,Tan DTH。眼睛的干细胞,Bongso A., Lee EH (Eds). Stem Cells: From Bench To Bedside. World Scientific 2005.

 

  1. Ang LPK、Abano J、Li L、Tan DTH。亚洲人眼睛的角膜移植,载于 Ang CL、Chee SP、Jap AH、Tan DT、Wong TY(编)。Clinical Ophthalmology: an Asian perspective. Elsevier 2005. P253-266.

 

  1. SE Ti、Ang LPK、Tan DTH。眼表疾病,载于 Ang CL、Chee SP、Jap AH、Tan DT、Wong TY(编)。 Clinical Ophthalmology: an Asian perspective. Elsevier 2005. P223-234.

 

  1. Ang LPK,Azar DT。LASEK 和 EpiLASEK。在:Yanoff M,Duker J(编)。 Ophthalmology, 4th Edition. Elsevier. 2012.

 

  1. Ang LPK,Azar DT。穿透性角膜移植术。在:Albert DM,Jakobiec FA (编)。 Principles and Practice of Ophthalmology, 3rdEdition Elsevier. 2007

 

  1. Ang LPK,Azar DT。眼表干细胞和伤口愈合对损伤和感染的反应。在:Albert DM,Jakobiec FA(编辑)。 Principles and Practice of Ophthalmology, 3rdEdition Elsevier. 2007

Millions of people around the world go blind from eye diseases every year. Of the five senses, sight is probably the most important of them all…

Millions of people around the world go blind from eye diseases every year. Of the five senses, sight is probably the most important of them all…

The eye has been termed the window to a person’s soul. It is a unique organ and is composed of many different types of tissue.

A Dialogue with a Doctor Interview Series: Lang Eye Centre Medial Director Dr. Leonard Ang

Glaucoma is the leading cause of irreversible blindness in the world, with an estimated 70 million…

As we know, not all lenses are created equal – and certainly, not all eyes are created equal. That leaves surgeons to balance the qualities,

Millions of people around the world go blind from eye disease every year. Sight is so important yet, many people take it for granted until it is lost.

Mdm X, a 57 year lady, noticed blurring of vision in both eyes for a few months. She saw Dr Leonard Ang, who found that her vision was poor and that she had dense cataracts in both eyes

Glaucoma is the second leading cause of blindness in the world and the leading cause of irreversible blindness. It is estimated that 7 million out of 70 million glaucoma patients worldwide suffer from bilateral blindness as a result of glaucoma.

The cornea is the central clear transparent window of the eye. Corneal blindness is one of the leading causes of treatable blindness, with more than 20 million cases happening globally

Refractive errors, such as myopia and presbyopia (lao hua), are common causes of poor vision. Advances in refractive surgery enable all forms of refractive error to be corrected, and patients can achieve excellent vision with greater precision and safety, without the need for spectacles

Retinal diseases such as age-related macular degeneration and diabetic retinopathy are 2 leading causes of blindness.

Myopia is also known as shortsightedness. This usually occurs when the eyeball is longer and light rays are focused in front of the retina.

Madam Zhang lost her right eye when a man splashed acid on her face during a robbery attempt in Johor Baru in 2007. She underwent a cornea transplant surgery in Malaysia for her remaining left eye which later developed a serious infection.

The eyes are the windows of the soul, it is said. They are also windows to your health, as are your nails, hair, tongue and gums.